Reciprocal Altered Expression of E-Cadherin and P-Cadherin in Mucous Membrane Pemphigoid
نویسندگان
چکیده
منابع مشابه
Autoregulation of E-cadherin expression by cadherin–cadherin interactions
Transcriptional repression of E-cadherin, characteristic of epithelial to mesenchymal transition, is often found also during tumor cell invasion. At metastases, migratory fibroblasts sometimes revert to an epithelial phenotype, by a process involving regulation of the E-cadherin-beta-catenin complex. We investigated the molecular basis of this regulation, using human colon cancer cells with abe...
متن کاملExpression of E- and P-cadherin in gastric carcinomas.
The expression pattern of two Ca2(+)-dependent intercellular adhesion molecules, E- and P-cadherin, in 54 surgically resected gastric adenocarcinomas was examined immunohistochemically. E-cadherin was expressed uniformly at the cell-cell borders of most of the differentiated and adherent-type undifferentiated gastric adenocarcinomas, showing that E-cadherin serves as the main cadherin molecule ...
متن کاملMucous membrane pemphigoid
Introduction Identifying risk factors for leprosy reactions can preempt clinicians to initiate prompt treatment to prevent associated morbidities. Thus, a retrospective study was done to elucidate the risk factors among 44 newly diagnosed leprosy patients in Sarawak General Hospital from 1993 to 2007. Materials and methods Case folders were searched for demographic data, clinical characteristic...
متن کاملExpression of P-cadherin, but not E-cadherin or N-cadherin, relates to pathological and functional differentiation of breast carcinomas.
AIMS To compare the expression of the cell adhesion molecules P-cadherin, N-cadherin, and E-cadherin in invasive and in situ breast carcinomas relative to clinicopathological features (size, node status, type, grade, and receptors) to determine whether expression patterns relate to specific tumour characteristics. METHODS Using immunohistochemistry, 110 invasive and in situ breast carcinomas ...
متن کاملImmunohistochemical Comparison of E-cadherin Expression in Oral Lichen Planus with and without Dysplasia
Objectives: E-cadherin is a transmembrane glycoprotein, which is responsible for cell adhesion and its expression decreases in dysplastic lesions. This study aimed to assess the expression of this marker in oral lichen planus (OLP) with and without dysplasia to assess its potential for use as a predictor of malignant transformation. Methods: This descriptive, cross-sectional study w...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Immunopathology and Pharmacology
سال: 2011
ISSN: 2058-7384,2058-7384
DOI: 10.1177/03946320110240s218